Title: Computational Tools for Modeling the Complex Dynamics of Biochemical Networks Speaker: Cranos M. Williams, North Carolina State University Date/Time: February 11, 2008 at 1:00 - 2:00pm (MST) 12:00 - 1:00pm (PT) Location: CSRI Building/Room 90 Sandia NM and videoconferenced to 915/S101 Sandia/CA Brief Abstract: Our inability to adequately model and simulate many complex dynamic systems is a result of a lack of computational tools that are capable of handling the added complexity that arises from nonlinear interactions at multiple scales of dynamic organization. This complexity contributes to our inability to identify appropriate mathematical representations that would advance our conceptual and theoretical understanding of the dynamics of these systems. This is particularly evident when attempting to understand the emergence of complex biological phenomenon from interactions that span many levels of biological organization. The complex properties of these systems limit the understanding that can be gained by traditional trial and error, reductionist, and experimental analyses. Specialize computational tools are required to better understand biological processes at a systems level, thus allowing researchers to attain the medicinal, nutritional, and social benefits that can be achieved through systematic modifications at various biological levels. My current research fits into a larger emerging research field known as systems biology. Specifically, it focuses on the development of computational tools that are designed specifically to model, analyze, and control complex biological systems across various levels of biological organization. Practical applications of this research include improved biosensors for pathogen detection, increased understanding of drug interactions resulting in fewer side effects, improved pharmaceuticals and nutraceuticals, alternative ways to synthesize biofuels, and the development of advanced bioprocessing techniques for waste reduction. CSRI POC: Scott Collis (1416) 284-1123 and Eric Phipps (1411) 284-9268 |