Sandia National Laboratoriessandia banner


Mike Brown

W. Michael Brown

Senior Member of the Technical Staff
Department 1412
Sandia National Laboratories
PO Box 5800
Albuquerque, NM 87185-1316

Adjunct Assistant Professor
Biochemistry and Molecular Biology
UNM School of Medicine
Basic Medical Sciences Building 249
Albuquerque, NM 87131

Contact
Phone: (505) 284-8938
Fax: (505) 845-7442
E-mail: wmbrown@sandia.gov
M/S: 1316

Education

Research Interests
Computer Science, Biomedical Sciences, Biochemistry

Research History
Curriculum Vitae
Publications (with links)

Some Current/Past Projects
Hybrid Evolutionary Optimization of Force-Field Functional Forms
Dimensionality Reduction in Molecular Physics and Informatics
Molecular Dynamics with Aspherical Particles for Nanoparticle Simulation
Supervised Learning from Molecular Dynamics - kernel Molecular Dynamics
Parallel Graph Drawing
Predicting Protein Function
Polymer Design
Optimal Representations for Neuronal Encoding
Beta-Strand Ordering in Ab-Initio Protein Structure Prediction
Information Content in Fragmental Descriptors
Structure Elucidation of Integral Membrane Proteins
The Macromolecule Encapsulating Surface - Docking, De Novo Design, and Binding Pockets
17-Beta-Hydroxysteroid Dehydrogenase as a Drug Target for Cancer
Lactacte Dehydrogenase as a Drug Target for Malaria

Software
Geryon (OpenCL, CUDA-RT, CUDA-Driver)
Dr. L (Dimensionality Reduction Library)
PM-Dreamer (Force-Field Fitting)

LAMMPS (Parallel Replica Dynamics, Aspherical Particle Simulation, GPGPU Acceleration)
ESSEB

Datasets
Data from PM-Dreamer Studies
Data from Dimensionality Reduction Studies
Data from kMD Studies
Structural database of linear homopolymers containing experimental data on Tg and PO2
Structures and activities for 120 inhibitors of urokinase plasminogen activator

Privacy & Security

Sandia Home Page

Sandia Home Page